Krebs Anhang 4
Krebs und Nahrung
Curcuma (+ schwarze Pfeffer)
Vollkornbrot
Rotwein
Tomaten
Gemüse (Kohl)
Zitrusfrüchte
Olivenöl
Öl (Omega-3-Fettsäure/Lein-/Olivenöl/Avocado/Mandeln)
Fisch (Hering/Thunfisch in Maße)
Tierische Produkten in Bioqualität
Dunkele Schokolade
Getränke: Wasser/grüne Tee
Sojaprodukte mäßig
Beere (Himbeere)
Caloric Restriction and Fasting in Disease Prevention and Treatment
Interview by Tina Kaczor, ND, FABNO
Interview with Valter Longo, PhD
Tina Kaczor, ND, FABNO, is senior medical editor of the Natural Medicine
Journal and is also a naturopathic physician, board certified in naturopathic
oncology. She received her naturopathic doctorate from National College of
Natural Medicine, and completed her residency in naturopathic oncology at
Cancer Treatment Centers of America in Tulsa, Okla. Dr. Kaczor received
undergraduate degrees from the State University of New York at Buffalo. She is
the current treasurer of the Oncology Association of Naturopathic Physicians
and secretary of the American Board of Naturopathic Oncology. She has been published in several
peer-reviewed journals.
Valter Longo, PhD, professor in gerontology, professor in biological
science, and director of the Longevity Institute, on his research in caloric
restriction and fasting in cancer. A member of the University of Southern
California (USC) Norris Cancer Center and USC Alzheimer’s Disease Research
Center. His laboratory is interested in understanding the fundamental mechanisms
of aging by using genetics and biochemistry techniques. It also seeks to
identify the molecular pathways conserved from simple organisms to humans that
can be modulated to protect against multiple stresses and prevent or treat
cancer, Alzheimer's disease, and other diseases of aging. The focus is on the
signal transduction pathways that regulate resistance to oxidative damage and
on the dietary changes that regulate them. Most projects in the lab include
parallel molecular studies in model organisms and mammals, with several
projects involving clinical trials and human population studies with focus on
dietary restriction and its effect on disease prevention and treatment.
Kaczor: For those not familiar with your work, it may seem
counterintuitive that caloric restriction can both prolong the life of
cells/organisms as well as hasten the death of cancer cells. Can you explain
how this seeming paradox works?
Longo: Fasting protects normal cells by causing entry into a
non-dividing stress resistance mode, which we have shown to be similar in
organisms ranging from yeast to humans. By contrast fasting makes it worse for
cancer cells by generating an extreme environment with low glucose and growth
factors and high ketone bodies, which weakens cancer cells. Each mutation in
cancer cells makes them a little better at growing under standard conditions,
but a little worse at surviving under extreme environments such as that caused
by fasting.
Kaczor: The ubiquitous role of fasting in various cultures and religions
around the world demonstrates that it is safe for humans. You published a
review that detailed what you called “metabolic, molecular and cellular
adaptations” from caloric restriction that ultimately may reduce the risk of
cancer. From your work, what is the optimal amount of caloric restriction, and
duration of that restriction, to achieve cancer preventative changes in humans?
Longo: I don’t think severe calorie restriction is appropriate since, in
addition to many beneficial effects, it also causes severe weight loss. I
believe that for now, a high micronourishment, mostly plant-based diet with
some fish that allows a BMI of 21–23 and low waist circumference is the ideal
diet. Brief periods of fasting followed by refeeding to remain at a steady
weight may also be recommended.
Kaczor: Your latest publication demonstrated sensitization the cytotoxic
effects of chemotherapeutics on mammalian cells in vitro through short-term
fasting. This was apparent for some cancers that have a poor prognosis
clinically, such as glioma. While the study was in vitro, many clinicians in
integrative medicine will be eager to hear if this is feasible in humans.
Cancer patients risk losing muscle mass, though, and maintenance of weight is
the priority in cancer care. The question for clinicians is how long of a fast
would be necessary to achieve possible sensitization of cancer cells to
chemotherapies? Is caloric restriction enough to achieve similar cellular
effects?
Longo: In both mice and patients, the great majority who fasted were
able to regain their weight after returning to the normal diet. For the 2–3
days of fasting (water only) before chemo and 24-hour fast (water only) after
chemo, the risk is minimal. However, patients with diabetes or metabolic
disorders, or those who have lost more than 10% of their weight, should be
carefully assessed before deciding whether fasting is appropriate for them.
Kaczor: Are there any agents, natural or pharmaceutical, that either
enhance the cellular changes seen in caloric restriction, or, conversely any
agents that may negate its benefits?
Longo: In response to the request of virtually every cancer patient who
tried fasting—but also in response to the low compliance among patients who
attempted to fast as part of the clinical trial at USC Norris Cancer Center—we
developed a substitution diet (Chemolieve, licensed to www.l-nutra.com) that
replaces fasting by obtaining the same effects or better compared to those of
fasting, while maximizing nourishment and minimizing cancer growth.
Fasting 'could help combat cancer and boost effectiveness of treatments'
Fasting slowed growth and
spread of tumours
Cured some cancers if combined
with chemotherapy
Human trials now under way
[Sadie Whitelocks]
Going without food for short periods may help to combat cancer and boost
the effectiveness of treatments, say scientists.
A study found fasting slowed the growth and spread of tumours and cured
some cancers when it was combined with chemotherapy.
It is hoped that the discovery will prompt the development of more
effective treatment plans and further research is now under way.
Fasting may help to combat cancer and boost the effectiveness of
treatment
The latest investigation, published in the journal Science Translational
Medicine, found that tumour cells responded differently to the stress of
fasting compared to normal cells. Instead of entering a dormant state similar
to hibernation, the cells kept growing and dividing, in the end destroying
themselves.
Lead researcher Professor Valter Longo, from the University of Southern
California said: 'The cell is, in fact, committing cellular suicide.
'What we're seeing is that the cancer cell tries to compensate for the
lack of all these things missing in the blood after fasting. It may be trying
to replace them, but it can't.'
Professor Longo and his team looked at the impact fasting had on breast,
urinary tract and ovarian cancers in mice.
Fasting without chemotherapy was shown to slow the growth of breast
cancer, melanoma skin cancer, glioma brain cancer and neuroblastoma - a cancer
that forms in the nerve tissue.
Scientists found tumour cells responded differently to the stress of
fasting compared to normal cells
In every case, combining fasting with chemotherapy made the cancer
treatment more effective.
Multiple cycles of fasting combined with chemotherapy cured 20% of those
with a highly aggressive form of cancer while 40% with a limited spread of the
same cancer were cured.
None of the mice survived if they were treated with chemotherapy alone.
Researchers are already investigating the effects of fasting on human
patients, but only a clinical trial lasting several years will confirm if human
cancer patients really can benefit from calorie restriction.
However they highlight that fasting could be dangerous for patients who
have already lost a lot of weight or are affected by other risk factors, such
as diabetes.
Results of a preliminary clinical trial will be presented at an annual
meeting of the American Society of Cancer Oncologists (Asco) in Chicago this
June.
Prof Longo points out that the study only tests if patients could
tolerate short fasts of two days before and one day after chemotherapy.
'We don't know whether in humans it's effective,' he said.
'It should be off-limits to patients, but a patient should be able to go
to their oncologist and say, 'what about fasting with chemotherapy?' or without
if chemotherapy was not recommended or considered.'
Previous research led by Prof Longo showed that fasting protected normal
cells from the effects of chemotherapy but it did not look at cancer cells.
It is now though fasting may be one way to make tumour cells weaker and
more vulnerable.
Prof Longo added: 'A way to beat cancer cells may not be to try to find
drugs that kill them specifically but to confuse them by generating extreme
environments, such as fasting, that only normal cells can quickly respond to.'
[Blanche Levine]
Has been a student of natural healing modalities for the last 25 years.
She has the privilege of working with some of the greatest minds in natural
healing including Naturopaths, scientist and energy healers. Having seen people
miraculously heal from all kinds of disease through non-invasive methods, her
passion now is to help people become aware of what it takes to be healthy.
Fasting Benefits (NaturalHealth365) The health benefits of fasting
should be learned by every oncologist in the world. You can actually kill
cancer cells with many different types of fasting techniques. Obviously, cancer
patients should work closely with a trusted, qualified healthcare professional
before attempting a fast of any kind.
Although not widely-known, studies have found that fasting slowed the growth
and spread of tumors and even eliminated the threat of cancer in some patients.
How does fasting help cancer patients?
If you think fasting is only for healthy people – you would be mistaken.
Scientific research suggests that cancer patients, undergoing chemotherapy
treatment, experienced a better outcome with less severe side effects. In fact,
you can find the latest news about how fasting helps chemotherapy patients in
the journal, Science Translational Medicine. Generally speaking, it seems like
fasting causes cancer cells to eventually destroy themselves during a carefully
monitored fast.
Professor Valter Longo, University of Southern California: “what we are
seeing is that the cancer cell tries to compensate the lack of all these things
missing in the blood after fasting. It may be trying to replace them, but it
can’t. The cell is, in fact, committing cellular suicide”.
Fasting can be one of many effective tools against cancer
With and without chemotherapy, fasting has been shown to slow the growth
of breast cancer; melanoma; certain brain cancers; and neuroblastoma – a cancer
that forms in the nerve tissue. However, across the board no matter what kind
it is – fasting has been shown to be effective.
Multiple cycles of fasting combined with chemotherapy cured 20% of mice
with a highly aggressive form of cancer while 40% of mice with a limited spread
of the same cancer were cured. By the way, research has found that none of the
mice survived – if they were treated with chemotherapy alone.
The health benefits of intermittent fasting
Fasting and calorie restriction are already known to boost health and
prevent many chronic health conditions. Keep in mind, there are several ways to
accomplish the life-extending benefits of fasting without skipping meals.
Long fasts should not be done unless under the care of a knowledgeable
health practitioner, but intermittent fasting has always been a part of
humankind.
Delaying a meal is not only easy but great for your health. Intermittent
fasting means to occasionally reduce or eliminate food intake for a short
period of time. Studies have found that when lab animals were allowed to eat
freely on every other day, they consumed the same number of calories as the
freely eating group. The difference is that the groups that fasted every other
day lived longer, had increased resistance to disease and improved insulin
sensitivity.
In human studies, when subjects fasted on alternate days, they lost
weight; reduced heart disease risk factors and slowed the growth of cancerous cells.
So, let’s take a closer look at different types of fasting techniques.
The 16 hour fast
For the beginner, the “16 hour fast” is probably the easiest way to go
with minimal effort. Try to eat all your meals during the day within an 8 hour
period of time. For example, you only eat from 9 - 5 h. – giving you 16 hours
of fasting time until your next meal. Try this for a few days and watch your
energy soar!
Creative ways to enjoy the benefits of fasting
You can also try to eat all your meals on one day and fast the next day.
This “alternating day” fast can be done for a week or more (depending on your
situation) with great results. By the way, the alternating day fast has been
shown to be highly effective with cancer and heart disease patients.
Obviously, the safest and easiest way to incorporate the benefits of
fasting into your everyday life is by drinking your food. Honestly, many people
have never felt better once they give their digestive system a rest from solid
food.
May I suggest that you treat yourself to a green juice fast. Some people
call this “juice feasting” – because you can have an 8 ounce glass of green
vegetable juice every hour – throughout the day.
If green juices don’t work for you – you may want to consider a day of
superfood smoothies. Usually, this will make you feel more satisfied and you
still get the benefit of giving your digestive system a rest from solid food.
Either way, your energy will feel amazing!
Be flexible and have some fun
For most individuals, a liquid fast is a great way to play around with
superfood nutrition. You can mix vegetables with a little fruit for a delicious
juice or mix in your favorite protein powder with herbs and spices for an
outstanding smoothie. Have you got a favorite juice or smoothie recipe? Post your
healthy creations below in the comment section.
Sources:
http://www.dailymail.co.uk/health/article-2098363/Fasting-help-combat-cancer-boost-effectiveness-treatments.html#axzz2K8C9T2ej
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