Mehrere Mittel
Vergleich: Siehe: Schmerzmittelgruppe + Schmerzmittel Anhang 5
Phenacetinum
(Phenac)
Gebrauch: Atemnot/schädigt Nieren;
Repertorium:
Kopf: Schmerz
Gesicht: bläulich
Hautausschläge
Fieber: Hitze im Allgemeinen
Typhus abdominalis
Allgemeines: Zyanose/Urämie
Vergleich: Hergestellt aus Anilin + Indg
Wirkung: euphorisierend/Fieber senkend/Schmerz lindernd/canceroid
Allerlei: zur Schmerzbehandlung und Fiebersenkung verwendet.
In 1887 eingeführt/in Arzneien gegen Migräne/Neuralgien/Rheuma Verwendung.
= Gesundheit schädigend (Nieren
schädigend)/seit 1986 nicht mehr im Handel. Ersetzt durch Paracetamol (= abgewandeltes Phenacetinum).
„Painkillers are widely used in the highly industrialized countries,
with analgesic-induced nephropathy remarkably common. 20% of patients requiring
dialysis present with analgesic-induced renal failure (Switzerland). At the
dialysis center in Luebeck, Germany, the figure is in the region of 10%. It is
not generally known that 10% of all patients with analgesic-induced renal
failure develop urothelial carcinoma. "Phenacetin kidney" first
described in 1950“.
[Christa-Johanna Bub-Jachens]
Analgesics with peripheral action - non-steroidal anti-inflammatory and
antipyretic drugs
The dangers of painkillers are often not fully recognized. They are
widely advertised, but potential consequences are only too rarely made known.
Painkillers are widely used in the highly industrialized countries, with
analgesic-induced nephropathy remarkably common. 20% of patients requiring
dialysis present with analgesic-induced renal failure (Switzerland). At the
dialysis center in Luebeck, Germany, the figure is in the region of 10%. It is
not generally known that 10% of all patients with analgesic-induced renal
failure develop urothelial carcinoma.
"Phenacetin kidney" was first described in 1950. In 1986, the
registration of drugs containing phenacetin was canceled. Concerning the
history of phenacetin: large quantities of p-nitrophenol were obtained as a
byproduct in the manufacture of certain pigments; the search for an industrial
use led to the development of phenacetin.
Anilines also have analgesic, anti-inflammatory and antipyretic properties
but proved too toxic. Acetanilide (an antipyretic), obtained by acetylation,
was in use for a long time before it was banned for causing methemoglobinemia.
In was known as early as 1887 that acetanilide converts to paracetamol
[N-(4-hydroxy-phenyl) acetamide] in the organism. "This substance is much
more effective and is better tolerated. Wanting to 'detoxify' paracetamol still
further, chemists produced the ethoxy compound phenacetin. Today we know,
therefore, that phenacetin is converted into paracetamol in the body."
The February, 1986 issue of Arznei-telegramm states: "The
pharmacological and toxicological data establish the same kind of nephrotoxic
and carcinogenic risk as for phenacetin. Epidemiological data that might go
against this are not available."
Today, we know that paracetamol, which has taken the place of
phenacetin, is no less nephrotoxic than phenacetin (in combination with
acetylsalicylic acid +/o. caffein.
All non-steroidal anti-inflammatory agents cause renal damage. The
histology shows non-purulent interstitial nephritis followed by papillary
necrosis. There is no dose-effect relation. Some patients taking large doses of
analgesics do not show damage, whilst others may develop nephropathy after even
relatively low doses. Generally speaking, it is true to say that renal damage
is all the more likely the higher the cumulative dose. Non-steroidal
antirheumatic drugs also play a considerable role in both chronic and acute
renal failure.
We note that these drugs have been produced from waste products.
R.S.: "It is not admissible simply to try substances out... without
considering what is revealed to the world in them. People test aspirin... or
phenacetin, etc., giving them to patients. If they give one after the other like
this, there is no need to activate the soul..." He described the way this
attitude had come from the Academy of Gondishapur and said there must be no
such science, devoid of all spirit, in the future. He spoke of the way
medicines were found by Intuition in the past, when people observed the inner
connections. Today scientists experiment and try substances out on a number of
people. Rudolf Steiner pointed out that such an approach would have negative
consequences in due course, though these would not have been noted by the
initial experimenters. Chemical analysis in the modem sense will not reveal the
world mission of a substance.
R.S.: it is important to know and perceive the relationship between
macrocosm and human being and that there is less and less such knowledge (in
medicine).
"I went through the martyrdom of the intellect and of sentience
when phenacetin was tried out. This method of trying something out, without
anything to guide one, shows that science has lost not only the spirit but also
its seriousness. .. .Today we must clearly distinguish where we have
caricatures of a science and where true insight is gained out of the
spirit." These words were spoken in 1908! Consider how long it took until
scientists discovered and admitted to facts which Rudolf Steiner had known
through the science of the spirit.
Analgesics with peripheral action inhibit prostaglandin synthesis and
thus prevent sensitization of pain receptors. Prostaglandins are hormone-like
substances involved in many processes (inflammatory processes and platelet
aggregation).
The question is, why do peripheral analgesics and anti-inflammatory
drugs cause kidney damage leading to kidney failure and urothelial carcinoma?
The kidney is a secretory organ which enables the human organism to become a
self-contained entity capable of self experience. Processes of conscious
awareness are connected with the kidney. The kidney is also the organ from
which the astral body radiates, which makes it the organic basis for
sentience.(9) Pain signifies increased awareness in the organic region
concerned. It is experienced in astral body and ego. (The pain vanishes as soon
as ego and astral body depart, e.g. in sleep, even if the wound is still
there.)
If we see pain as something that brings awareness, waking us up, we may
also consider it to be our helper, a chance to perceive the need for specific
measures both externally and inwardly. If this awareness-creating symptom is
simply suppressed, with no other suitable measures taken, this may create deep-seated
problems for the individual concerned.
Apart from kidney damage, potential side effects of all the types of
drugs mentioned above include hypersensitivity (skin reactions,
analgesic-induced asthma, etc.) and changes in blood profile (agranulocytosis).
It is evident that a shift occurs in the astral body's direction of action and
also an attack on the ego-organization.
The above-mentioned drugs not only eliminate pain but also have
anti-inflammatory and antipyretic properties. Relative to reduced awareness,
the suppression of inflammatory reactions and the effect on the warmth
organization are of much greater account. They add to the damaging effects of
modem civilization, increasing the diseases of our time.
The question is, what is the effect of drinks containing paracetamol
used to treat colds (Contac Night-Time, Larylin, and others)? They sound so
harmless and are used with terrible frequency. What does it mean if we use
acetylsalicylic acid to treat inhibition of platelet aggregation, which is a common
practice today?
Paracetamol
= Schmerzmittel
Gebrauch: Nieren-/Leberschäden;
„International Study of Asthma and Allergies in Childhood“, veröffentlicht im Fachjournal „The Lancet“ (2008 Sep 20;372(9643):1039-48.) kam zu dem Ergebnis, dass zwischen der Verabreichung von Paracetamol bei Fieber im ersten Lebensjahr und Asthma-Symptomen bei den sechs- und siebenjährigen Kindern ein Zusammenhang besteht: Nach Paracetamol-Einnahme erhöhte sich das Asthma-Risiko um bis zu 38%!
Verursacht Störungen bei Kindern wann von Mutter genommen in der Schwangerschaft.
Vergleich: Phenacetinum (= Ausgangsstoff Paracetamol)
Antidotiert von: Überdosis: ACC.
Allerlei: Entwickelt in 1887
Vorwort/Suchen Zeichen/Abkürzungen Impressum