Medhorrinum Anhang 2
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[Frans Vermeulen]
II. ORDER
NEISSERIALES
IIA. FAMILY
NEISSERIACEAE
Neisseria gonorrhoeae
Neisseria meningitidis
Neisseria subflava
Neisseria catarrhalis
GENUS
NEISSERIA
• Gram-negative, oxidase-positive, aerobic or
facultative anaerobic cocci characteristically coffee bean-shaped and paired.
• Part of the normal flora of oropharynx,
nasopharynx, and genitourinary tract.
• The genus includes saprophytic as well as
pathogenic species.
• Many species in the genus have been isolated
from animals:
Neisseria animalis
Neisseria canis
Neisseria caviae - found in the pharyngeal
region of apparently healthy guinea pigs.
Neisseria cuniculi - rabbits.
Neisseria dentiae - found in the dental plaque of
domestic cows.
Neisseria iguanae - iguanid lizards.
Neisseria macacae - from the oropharynges of
rhesus monkeys.
Neisseria ovis - associated with infectious
keratoconjunctivitis of sheep.
Neisseria weaver! - commensals in the mouth and
nasopharynx of cats and dogs; human infection may occur from a cat or dog bite.
GENUS:
Neisseria SPECIES: N. gonorrhoeas Med.
NEISSERIA
GONORRHOEAE
Neisseria gonorrhoeae (Zopf 1885) Trevisan 1885
Micrococcus der gonorrhoe Neisser 1879
Merismopedia gonorrhoeae Zopf 1885
Micrococcus gonorrhoeae (Zopf 1885) Fliigge
1886
Micrococcus gonococcus Schroeter 1886
Diplococcus gonorrhoeae (Zopf 1885) Lehmann and
Neumann 1896
Gonococcus neisseri Lindau 1898
Gonococcus
Neisseriaceae
Medorrhinum - Med.
Medorrhinum Americana - Med-am. [not in
repertory]
• Occurs
typically as non-motile pairs of flattened cells.
• First
observed in urethral and conjunctival secretions of gonorrhoea and purulent
ophthalmia by the German dermatologist Albert Neisser in 1876.
• Found
primarily in purulent venereal discharges. "Can be found in the urethral discharges
of gonorrhoea from the beginning till the end of the disease, and often for
many months and even years after recovery from it”. [McFarland]
•Considered
a pathogen of human origin.
• Requires
5-10% carbon dioxide and a humid atmosphere. Does not survive dehydration and
cool conditions.
• Ferments
glucose but not maltose ["sugar and sex, but no beer"].
• Leading
cause of septic arthritis in adults.
•Gonococcal
infections are 1.5 times as common in men than in women, although serious
sequelae are much more common in women.
• Small
quantities of "gonotoxin" introduced into the urethra cause suppuration
at the point of application, fever, swelling of the adjacent lymphatic nodes,
and muscular and articular pains. [McFarland]
DISSEMINATED
GONOCOCCAL INFECTION
Disseminated
gonococcal infection [DGI] occurs following approximately 1% of genital
infections. It is seen more frequently in women, especially during menstruation
and pregnancy.
Patients
with DGI may present with symptoms of rash, fever, arthralgias, migratory
polyarthritis, septic arthritis, endocarditis, or meningitis. Joint or tendon
pain is the most common presenting complaint.
About 25%
of patients with DGI complain of pain in a single joint, while up to 2/3 describe
polyarthralgia (migratory). Severe pain, swelling, and decreased mobility in a
single joint suggest a purulent arthritis with effusion.
The knee is
the most common site of purulent gonococcal arthritis.
Tenosynovitis
also is common, usually affecting the small joints of the hands.
Skin rash
is a presenting complaint in approximately 25% of patients, but a careful
examination will reveal a rash in the majority of patients with DGI, incl.
maculopapular, pustular, necrotic, or vesicular rash, typically occurring
on the
torso, limbs, palms, and soles. The rash usually spares the face, scalp, and
mouth. Haemorrhagic lesions, erythema nodosum, urticaria, and erythema
multiforme occur less frequently. Headache, neck pain and stiffness, fever,
and
decreased sensorium may indicate gonococcal meningitis. This disease may be
clinically indistinguishable from meningococcal meningitis on presentation, although
the course of gonococcal meningitis usually is less rapid
than that
of meningococcal meningitis. Gonococcal endocarditis is more common in men than
women. Patients with collagen vascular disease [systemic lupus erythematosus]
also may be more prone
to this
complication. DGI can cause abscess formation within the soft tissues,
presenting
as localized tenderness, oedema, and pain with motion. [Behrman, Gonococcal
infection; website University of Pennsylvania Medical Center]
MATERIA
MEDICA MEDORRHINUM Med.
Proved by
Swan & Berridge [collection of provings] — 45-50 provers [about 50% females
and 50% males], c. 1888; method: various high potencies, such as 1M, 10M, 20M,
40M, 60M, and MM; manner not stated; contains
also cured
symptoms.
Graffiti on
the London Underground: Life is a sexually transmitted disease.
Repertory:
Mind: Time and space. Times passes too
slowly.
Hurry;
always in a rush and anticipating, yet lacking the desire for realisation.
Lacks
clear-set goals; chases shadows. Hurry, everybody seems to move too slowly.
Anxiety if a time is set. Everything feels far off. Objects seem small.
Dazed
dreaminess, as if'stoned'.
fulfilment
- emptiness. Everything seems unreal. Sensation of unbearable inner emptiness.
Vacant staring.
Easily
bored. 'Attention junkies; party animals.'
Forgetful;
confused - common things escape him.
Seems to
herself to make wrong statements because she does not know what
to say
next; begins all right but does not know how to finish [Grimmer]
Extremes;
exceeding all limits. No boundaries; lack of orientation points. Chasing shadows
or chased by shadows.
Bouts of
hopelessness alternating with episodes of hopeful optimism.
Strokes of
genius or inexplicable blackouts.
Extroversion
- introversion. Wild feeling in head or vacant feeling in head. Clair-obscure:
lucid after sunset, obscure after sunrise. Arrhythmia.
VECTOR
Human
Found in
mouth, nose, throat, genital and urinary tracts.
Shuns
responsibilities.
Generals
« Craves
fresh air.
« Feels
better in evening/night. Night person.
» Seaside
>.
~ Lying on
abdomen or in knee-elbow position >. Desire to cross the ankles when lying
on the back. ~
Great
thirst.
= Desire
for sweets, green fruits, ice, acid foods, salt. = Craves beer; alcohol;
tobacco.
Walks on
sides of feet [due to extreme sensitivity of soles of feet].
Local heat
- coldness
= Boiling
sensation in head.
= Burning
hands and feet; wants them uncovered.
» Heat in
eyelids.
= Hot
flashes cervical region.
= Severe
burning in the base of the tongue, extending down the bronchi “As if inhaled
hot steam”
= Sensation
of coldness in eyes, as if cold air blew on them. = Coldness of tip of nose;
breasts, esp. nipples; abdomen; liver region; right lumbar region. =»
Chilliness on urging to urination; before urination.
Discharges
=
Discharges >.
«
Discharges mucopurulent or purulent; yellowish-green or yellowish-white.
« Fishy
odours.
= Yellowish
staining sweat. Greasy face.
<=
Pungent body odour; penetrating pungent odour to stool.
Affinities
Since the
drug picture of Medorrhinum is partly based on cured cases of gonorrrhoea, the
classic complications of gonococcal infections may be expected to present
themselves in the drug picture. Above all this concerns
Pelvic
Inflammatory Disease [PID], characterised in women by infertility, PMS,
purulent vaginal discharge, uterine tenderness, intermenstrual bleeding, menorrhagia,
enlarged tubes, elevated temperature, urinary tract infections,
Dysuria (bilateral
lower abdominal pain with nausea and vomiting).
Due to
painful genital swelling difficulty in walking may develop.
Intrauterine
devices [IDDs] significantly aggravate PID; hence intolerance of
GENUS:
Neisseria SPECIES: N. gonorrhoeas Med.
IUD (=
Pessar) may be an indication for Medorrhinum, if symptoms agree. There is an
increased risk of ectopic pregnancy. Epididymitis-orchitis is the male equivalent
of PID.
Acute
infectious arthritis occurs somewhat more often in women, with menstrual
periods and pregnancy as the most common triggers. Most have joint pains or
tenosynovitis involving wrists, knees, ankles and small joints
of hands
and feet, in combination with skin eruptions, which consist of petechial-pustular
lesions on an erythematous base. After a migratory stage the pain/inflammation
usually settles in a "hot joint," commonly the knee.
Pharyngitis
is also frequently observed, as are proctitis and conjunctivitis.
Proctitis
may present with minor symptoms such as pruritus, pain, pressure, fulness, mild
diarrhoea or discharge, or mucus on stools. Less frequently more severe
symptoms are present, such as tenesmus, purulent discharge,
and
bleeding. Conjunctivitis presents with pain, chemosis, oedema of lids, and
purulent yellow discharge.
Medorrhinum
symptoms such as "sensation of a tumour in the right side of abdomen,"
"grasping pain in liver," and "pain extending from liver to
right shoulder," show a similarity with gonococcal perihepatitis
[Fitz-Hugh-Curtis
syndrome]
observed in women with a history of gonorrhoeal salpingitis.
The
syndrome consists of acute upper right-quadrant abdominal pain and tenderness
aggravated by breathing, coughing, or movement, with pain ext. to the right
shoulder.
Children
Based on 37
case histories, Jutta Gnaiger-Rathmanner and Mirjam Bohle provide a summary of
indications for the treatment of "allergic and nervous children" with
Medorrhinum.
All of
these children, mostly boys, love to move, happy whenever they can ramble
outdoors. They love practical things, and feel extremely bored by the requirements
at school. Often the intensity on the one hand and the flightiness
and
contrariness on the other hand lead to the selection of the remedy.
Often
having a sensation of heat they like to undress and sleep uncovered. In early
childhood striking or hitting seems to be an important form of expression when
other ways to express themselves are not accessible.
In school
the aggression seems to be reactive - they are followers, ready to join every
nonsense.
If there is
a storm centre, they follow without hesitation. Mostly the leaders are other
children. One often hears the mother say, 'I don't understand his behaviour at
school. If he is alone with me, he is obedient and a good boy.'
Medorrhinum-boys
charm their mothers - possibly in competition with their fathers?
Medorrhinum-boys
feel attracted to girls in a premature and excessive way?
Prematurity
manifests itself as: = Vigorous denial of all kinds of conformity and book
learning, long before puberty.
Great interest
in all kinds of technology.
=
Precocious curiosity for fashion, trends and eroticism.
The
clairvoyance of these children is revealed by their ability to detect every weakness
and tension in their surroundings. They are the children who unerringly expose
adults to ridicule. The negative and disharmonious
moments of
life inevitably attract them.
Regarding
early infantile development, many remarkable deviations are found.
Also these
children present very particular disabilities, such as attention deficit disorder.
A whole
string of symptoms in the Medorrhinum picture corresponds with this:
= Sleep position genupectoral.
= Opisthotonus.
= Motions of head - rolling head.
= Awkwardness.
= Lack of perseverance.
= Concentration difficult.
= Makes mistakes - in writing; speaking;
spelling; in time.
Regarding
symptoms such as 'ailments from reproaches,' 'sensitive to reprimands,' and
'despair from the slightest criticism,' it should be noted that these children
need encouragement and real help, not criticism. Jealousy of
siblings;
quarrels in the family; overcharge at school; heavy competition at school, are
mentioned as causations observed by the authors. The main symptom
'restlessness' culminates in symptoms such as biting nails,
masturbation,
facial twitching, and various sleep disorders. Furthermore there is a tendency
to dyslexia. Left-handedness as well as refusal to go to school are frequently
observed, the latter being the result of learning disabilities
and impaired
co-ordination of movement. Common physical complaints include litis, putrid
otitis, gastro-enteritis, or dry spasms including laryngitis and asthmatic
bronchitis. There is high fever during infections or no fever at all.
Food
intolerances, in particular to milk, may lead to fussiness about food and a
bias towards monotonous nutrition. Cravings change frequently, but always with
the same intensity to exclude/refuse everything else.
[Adapted from: Jutta Gnaiger-Rathmanner and Mirjam Bohler, Medorrhinum – a remedy for modern children; Horn. Links 2/03]
Vorwort/Suchen Zeichen/Abkürzungen Impressum