Radioaktivitδt Anhang
Apple Pectin
Removal of
Radionuclides from the Body
The
curative-like use of apple-pectin food additives might be especially helpful
for effective decorporation of Cesium-137. From 1996 to 2007 a total of more
than 160,000 Belarussian children received pectin food additives during 18 to
25 days of treatment (5 g 2x dailyy). As a result, levels of Cesium-137 in
childrens organs decreased after each course of pectin additives by an average
of 30 to 40%.
Manufacture
and application of various pectin-based food additives and drinks (using
apples, currants, grapes, sea seaweed, etc.) is one of the most effective ways
for individual radioprotection (through decorporation) under circumstances
where consumption of radioactively contaminated food is unavoidable.
http://www.ncbi.nlm.nih.gov/pubmed/20002057
L-Carnitine
( a naturally occurring amino acid)
Comparison
of protective effects of L-carnitine and amifostine on radiation-induced
toxicity to growing bone: histopathology and scintigraphy findings.
L-carnitine
is equally as effective as amifostine at protecting growing bone against single
dose irradiation damage
http://www.ncbi.nlm.nih.gov/pubmed/21039033
Iodine
Supplements
Radiation-induced
thyroid cancer
Radioactive
iodine, especially 131I, may be released into the environment as a result of
nuclear reactor accidents. Thyroid accumulation of radioactive iodine increases
the risk of developing thyroid cancer, especially in children. The increased
iodine trapping activity of the thyroid gland in iodine deficiency results in
increased thyroid accumulation of radioactive iodine (131I). Thus,
iodine-deficient individuals are at increased risk of developing
radiation-induced thyroid cancer because they will accumulate greater amounts
of radioactive iodine. Potassium iodide administered in pharmacologic doses
(50-100 mg for adults) within 48 hours before or eight hours after radiation
exposure from a nuclear reactor accident can significantly reduce thyroid
uptake of 131I and decrease the risk of radiation-induced thyroid cancer. The
prompt and widespread use of potassium iodide prophylaxis in Poland after the
1986 Chernobyl nuclear
reactor
accident may explain the lack of a significant increase in childhood thyroid
cancer in Poland compared to fallout areas where potassium iodide prophylaxis
was not widely used. In the U.S., the Nuclear Regulatory Commission (NRC)
requires that consideration be given to potassium iodide as a protective
measure for the general public in the case of a major release of radioactivity
from a nuclear
power plant.
Food
sources of Iodine
Food
sources of iodine in mcg : Salt (iodized) 1 gram 77mcg,
Egg, boiled 1 large 12mcg, Navy
beans, cooked 1/2 cup 32 mcg, Potato with peel, baked 1 medium 60 mcg, Turkey breast, baked 3 ounces 34 mcg, Seaweed 1/4 ounce, dried Variable; may be
greater than 4,500 mcg (4.5 mg).
http://lpi.oregonstate.edu/infocenter/minerals/iodine/
Beta 1,3,
Glucan Derived from Bakers yeast
Beta-1,3-glucans
radiation protection effects were shown in 1985 when the U.S. Armed Forces
Radiobiology Research Institute announced the results of their recent
experiments.
Myra D.
Patchen, M.D., and her team at the Institute exposed mice to lethal doses of
radiation.
When the
mice were given an oral dose of beta-1,3-glucan after the radiation exposure,
70% were completely protected from the damaging effects. Dr. Patchen also
suggested that beta-1,3-glucan
should be
considered as an effective way of rebuilding the immune system and preventing
infection following chemotherapy and radiation in cancer treatment. Dr. Patchen
further suggested that beta-1,3-glucan appears to work as a free-radical
scavenger (anti-oxidant) and may even protect the macrophages from damage by
radiation, toxins, heavy
http://www.betaglucan.org/history.htm
Vitamin C
Ascorbic
acid gives different protective effects in human cells exposed to X-rays and
heavy ions.
http://www.ncbi.nlm.nih.gov/pubmed/20394838
N: Acetyl
Cysteine (NAC)
Protective
effect of N-acetylcysteine against radiation induced DNA damage and hepatic
toxicity in rats.
Results
show that pretreatment with N-acetylcysteine offers protection against
gamma-radiation induced cellular damage.
http://www.ncbi.nlm.nih.gov/pubmed/18028880
also
Effect of
N-acetylcysteine on radiation-induced genotoxicity and cytotoxicity
in rat bone marrow.
http://www.ncbi.nlm.nih.gov/pubmed/19218780
Green tea
polyphenols
Bioactive
components from the tea polyphenols influence endogenous antioxidant defense
system and modulate inflammatory cytokines after total-body irradiation in
mice.
http://www.ncbi.nlm.nih.gov/pubmed/21498061
Phytomedicine.
2011 Apr 15. [Epub ahead of print]
Hu Y, Guo
DH, Liu P, Cao JJ, Wang YP, Yin J, Zhu Y, Rahman K.
Source
Dept. of Clinical Pharmacology and Pharmacy, Centre of Pharmacy, Chinese PLA
General Hospital, Beijing 100853, China.
Abstract
The present study aimed to evaluate the radioprotective efficacy of green tea
polyphenols and the component ingredients against irradiated-induced damage in
mice and elucidate the underlying mechanisms.
GTP and its bioactive components (catechin, epigallocatechin and
epigallocatechin-3-gallate) assisted in decreasing the leukocytopenia seen
after whole mice irradiation and significantly reduced the elevated serum
inflammatory cytokines (TNF-?, IL-1?, and IL-6). Green tea polyphenols have a
potential to be developed as radioprotective agents against irradiated-induced
toxicity.
Phytochemicals
Protection
against ionizing radiation by antioxidant nutrients and phytochemicals
Weiss JF,
Landauer MR.
Office of
Health Studies, US Department of Energy, EH-6/270 Corporate Square, 1000
Independence Avenue, SW, Washington, DC 20585-0270, USA.
joseph.weiss@eh.doe.gov
Results
from animal experiments indicate that antioxidant nutrients, such as vitamin E
and selenium compounds, are protective against lethality and other radiation
effects but to a lesser degree than most synthetic protectors. Some antioxidant
nutrients and phytochemicals have the advantage of low toxicity although they
are generally protective when administered at pharmacological doses. Naturally
occurring antioxidants also may provide an extended window of protection
against low-dose, low-dose-rate irradiation, including therapeutic potential
when administered after irradiation. A number of phytochemicals, including
caffeine, genistein, and melatonin, have multiple physiological effects, as
well as antioxidant activity, which result in radioprotection in vivo.
http://www.ncbi.nlm.nih.gov/pubmed/12821279
Water
soluble Vitamin E (TMG) as a Radioprotector.
Tocopherol
monoglucoside (TMG), a water soluble derivative of vitamin E offers protection
against deleterious effects of ionizing radiation
Embryonic
mortality resulting from exposure of pregnant mice to ionizing radiation (2 Gy)
was reduced by 75% by ip administration of TMG (0.6 g/kg, body wt) prior to
irradiation. TMG offered protection to mice against whole body
gamma-radiation-induced lethality and weight loss. The LD50(30) of mice
increased from 6 to 6.72 Gy upon post irradiation administration of a single
dose of TMG (0.6 g/kg, body wt) by ip.
http://www.ncbi.nlm.nih.gov/pubmed/15320488
Radioprotective
potential of ginseng (genus Panax)
This review
addresses the issue of the radioprotective effects of ginseng on mammalian
cells both in vitro and in vivo. Results indicate that the water-soluble
extract of whole ginseng appears to give a better protection against
radiation-induced DNA damage than does the isolated ginsenoside fractions.
http://www.ncbi.nlm.nih.gov/pubmed/15956041
GINKO
Protective
effect of Ginkgo biloba against radiation-induced cellular damage in human
peripheral lymphocytes and murine spleen cells
International
Journal of Low Radiation, 2009, 6, 209-218.
The data
demonstrated that EGb, through its free-radical scavenging and antioxidant
properties, attenuates IR-induced apoptosis in radiosensitive cells, suggesting
that EGb may have a potential benefit in enhancing radioprotective effects.
http://www.inderscience.com/search/index.php?action=record&rec_id=28889
Spirulina
A 1989
study put forth by researchers from Zhongkai Agriculture and Technology College
in China found in tests that Spirulina significantly reduces the gamma
radiation-induced micronucleus frequencies in the bone marrow of affected mice.
Bone marrow, of course, is responsible for producing new blood cells and
maintaining the lymphatic system (http://www.ncbi.nlm.nih.gov/pubmed/
).
PEONY
Chinese Herb
Protective
effect of paeoniflorin on irradiation-induced cell damage involved in
modulation of reactive oxygen species and the mitogen-activated protein
kinases.
http://www.ncbi.nlm.nih.gov/pubmed/17097910
The
objective of this study was to investigate the radioprotective effect of
paeoniflorin (PF, a main
bioactive
component in the traditional Chinese herb peony
GARLIC
In vivo
radioprotection with garlic extract
Garlic
extract was evaluated in the mouse bone marrow micronucleus test for its
possible protective effects against gamma-radiation-induced chromosomal
damage.. The irradiated garlic-extract pre-treated animals showed a significant
reduction in sulfhydryl content and glutathione S-transferase activities
Mutat Res.
1995 Dec;345(3-4):147-53. Singh SP,
Abraham SK, Kesavan PC.
Source
School of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
http://www.ncbi.nlm.nih.gov/pubmed/8552136
Citrus
extract
Radioprotective
effects of citrus extract against gamma-irradiation in mouse bone marrow cells.
The
radioprotective effects of citrus extract were investigated by using the
micronucleus test for anticlastogenic and cell proliferation activity. The flavonoids contained in citrus extract
reduced the clastogenic effect of radiation on mice bone marrow. Therefore
fruits and vegetables containing flavonoids
may be useful under such stress conditions as irradiation.
J Radiat
Res (Tokyo). 2003 Sep;44(3):237-41.
Hosseinimehr SJ, Tavakoli H, Pourheidari G, Sobhani A, Shafiee A.
Source
Department of Medicinal Chemistry, Faculty of Pharmacy, Mazandaran University
of Medical Sciences, Tehran, Iran. sjhosseinim@yahoo.com
http://www.ncbi.nlm.nih.gov/pubmed/14646227
Miso
Radioprotective
effects of miso (fermented soy bean paste) against radiation in B6C3F1 mice:
increased small intestinal crypt survival, crypt lengths and prolongation of
average time to death.
http://www.ncbi.nlm.nih.gov/pubmed/11833659
Hiroshima J Med Sci. 2001 Dec;50(4):836.
Ohara M, Lu
H, Shiraki K, Ishimura Y, Uesaka T, Katoh O, Watanabe H.
Source
Department of Environment and Mutation, Research Institute for Radiation
Biology and Medicine, Hiroshima University, Japan.
Abstract The radioprotective effect of miso, a
fermentation product from soy bean, was investigated with reference to the
survival time, crypt survival and jejunum crypt length in male B6C3F1 mice. Miso
at three different fermentation stages (early-, medium: and long-term fermented
miso) was mixed in MF diet into biscuits at 10% and was administered from 1
week
before
irradiation. Animal survival in the long-term fermented miso group was
significantly prolonged as compared with the short-term fermented miso and MF
cases after 8 Gy of 60Co-gamma-ray irradiation at a dose rate of 2Gy min(-1). Delay
in mortality was evident in all three miso groups, with significantly increased
survival. At doses of 10 and 12 Gy X-irradiation at a dose rate of 4 Gy
min(-1), the treatment with long-term fermented miso significantly increased
crypt survival. Also the protective influence against irradiation in terms of
crypt lengths in the long-term fermented miso group was significantly greater
than in the short-term or medium-term fermented miso and MF diet groups. Thus,
prolonged fermentation appears to be very important for protection against
radiation effects.
Mint
Radioprotective
potential of mint: a brief review.
Mentha
piperita and M. arvensis protected mice against the ?-radiation-induced
sickness and mortality.
http://www.ncbi.nlm.nih.gov/pubmed/21119249
Tulsi
(Herb)
Ocimum
tenuiflorum (also tulsi, tulas?, or Holy Basil)
Tulsi is
cultivated for religious and medicinal purposes, and for its essential oil. It
is widely known across South Asia as a medicinal plant and an herbal tea. It
also shows some promise for protection from radiation poisoning.
Note:
Contraindications: Holy Basil should not be taken while pregnant or nursing or
for an extended period of time. Use caution if you have high blood pressure or
rheumatic heart disease.
Devi, P. Uma;
Ganasoundari, A.. Modulation
of glutathione and antioxidant enzymes by Ocimum sanctum and its role in
protection against radiation injury. Indian Journal of Experimental Biology,
v.37, n.3, 1999. March,:262-268.
http://www.ncbi.nlm.nih.gov/pubmed/10641157
Echinacea
(E.) purpurea
This herb
is commonly known as the purple coneflower.
Phytotherapeutic
effects of Echinacea purpurea in gamma-irradiated mice.
http://www.ncbi.nlm.nih.gov/pubmed/17993747
Milk
Thistle Extract
Radioprotection
of plasmid and cellular DNA and Swiss mice by silibinin
Tiwari P, Kumar
A, Ali M, Mishra KP.
Source
-Radiological Physics and Advisory Division, Bhabha Atomic Research Centre,
Mumbai 400 085, India. Mutat Res. 2010 Jan;695(1-2):55-60. Epub 2009 Nov 27.
Abstract -The radioprotective effect of a non-toxic
bioactive component in plant milk thistle, silibinin against genotoxicity
induced by gamma-irradiation was investigated in vivo/in vitro. Our extended animal studies suggest that oral
administration of silibinin (70mg/kg for 3 days)
to mice
prior to whole-body gamma-exposure (7.5Gy) resulted in significant protection
to radiation-induced mortality and DNA damage in blood leukocytes. However,
silibinin treatment after irradiation was not as effective as
pre-administration.
http://www.ncbi.nlm.nih.gov/pubmed/19945544
Hesperidin
Evaluating
the radioprotective effect of hesperidin in the liver of Swiss albino mice.
http://www.ncbi.nlm.nih.gov/pubmed/21371459
Propolis
Concentration-Dependent
Protection by Ethanol Extract of Propolis against ?-Ray-Induced Chromosome
Damage in Human Blood Lymphocytes.
A
significant and concentration-dependent decrease is observed in the frequency
of chromosome aberrations in samples treated with EEP (ethanol extract of
propolis)..
http://www.ncbi.nlm.nih.gov/pubmed/20981159
Citrus
Bioflavonoids
Naringin, a
citrus flavonone, protects against radiation-induced chromosome damage in mouse
bone marrow
Ganesh
Chandra Jagetia1, V.A. Venkatesha and Tiyyagura Koti Reddy
Department
of Radiobiology, Kasturba Medical College, Manipal 576 119, India
The aim of
the present study was to evaluate the radioprotective action of 2 mg/kg
naringin in the bone marrow of mice exposed to different doses of 60Co
??radiation. Treatment of mice with 2 mg/kg body wt naringin before exposure to
various doses of ??radiation resulted in a significant reduction in the
frequencies of aberrant cells and chromosomal aberrations like acentric
fragments, chromatid and chromosome breaks, centric rings, dicentrics and
exchanges. Our study demonstrates that naringin can protect mouse bone marrow
cells against radiation-induced chromosomal damage.
http://www.ncbi.nlm.nih.gov/pubmed?term=Naringin%2C%20a%20citrus%20flavonone%2C%20protects%20against%20radiation
Chlorella
The
radioprotective effects of aqueous extract from chlorococcal freshwater algae
(Chlorella kessleri) in mice and rats.
http://www.ncbi.nlm.nih.gov/pubmed/2688154
Alginic
acid and Alginate (found in seaweed)
Biomaterials
for the decorporation (removal) of (85)Strontium in the rat.
Health
Phys. 2010 Sep;99(3):394-400.
Levitskaia
TG, Creim JA, Curry TL, Luders T, Morris JE, Peterson JM, Thrall KD.
Pacific
Northwest National Laboratory, PO Box 999, MSIN P7-22, Richland, WA 99352, USA.
Tatiana.levitskaia@pnl.gov
Strontium
is chemically and biologically similar to calcium, and is incorporated
primarily into bone following internal deposition. Alginic acid (alginate)
obtained from seaweed (kelp) extract selectively binds ingested strontium in
the gastrointestinal tract blocking its systemic uptake and reducing
distribution to bone in rats. Alginate exhibits the unique ability to
discriminate between strontium and calcium and has been previously shown to
reduce intestinal absorption and skeletal retention of strontium without
changing calcium metabolism.
http://www.ncbi.nlm.nih.gov/pubmed/20699703
[Dr. Rajneesh K. Sharma]
Homeopathic
Remedies for Radiation Effects
These
homeopathic remedies are not suggested as prophylaxis and as always, must be
chosen on the symptom complex. This is only a sample of the possible remedies.
Rad-br.:
Aching PAIN and restLESS. Anxious, fear of being alone in the dark and desires
company. Dreams of fire. Violent
cramping in abdomen. Severe pain in all limbs. Itching all over body. Necrosis
and ulceration. Internal chill with heat of skin.
Cadm-s.:
Terrible nausea, black vomit, freezing cold and cant get warm. Also vomits
green mucus, blood, or coffee grounds. Bloody-black offensive stools. Extreme
exhaustion.
Ip.:
Constant nausea not relieved by vomiting. Bloody slimy stools. Bleeding from
lungs with nausea. Tongue clear. Profuse salivation and thirstless. <
slightest motion/warmth.
Phos.:
Bleeding bright red blood from any orifice. Craves ice cold drinks but vomits
them soon after. Heightened sensitivity to noise, odors, lights and startles
easily. Fear of being alone. Exhausting diarrhea.
Ars.:
Anxious, chilly, restless, exhausted, thirsty for small sips. Burning pain >
heat, fear of being alone, < after midnight.
X-ray.:
Stiff neck, sticking pains in head and face. Nausea, rheumatic pain, tired,
sick feeling. Tongue dry, rough , sore.
Dry skin and painful cracks. Chronic itching eruptions.
Gins.
Ruta
White mice
were exposed to X radiation with a power of 100 to 200 rad (non lethal dosage)
and were then evaluated after 24, 48 and 72 hours. Ginseng 6X, 30CH and 200CH
and Ruta graveolans 30CH and 200CH were given before and after the radiation. In
comparison to mice who received placebo, those who were administered with
homeopathic medicines presented significantly less damage in cells and
chromosomes.
(A.R.
Khuda-Bukhsh, S. Banik, Assessment of Cytogenetic Damage in X-irradiated Mice
and its Alteration by Oral Administration of Potentized Homeopathic Drug, Ginseng
D200, Berlin Journal of Research in Homeopathy, 1991, 1,4/5:254. Also
Khuda-Bukhsh, A.R. Maity, S., Alteration of Cytogenetic Effects by Oral
Administration of Potentized Homeopathic Drug, Ruta graveolens in Mice Exposed
to Sub-lethal X-radiation, , 1991, 1, 4/5:264).
Repertory
of Radiation effects:
Toxicity: ailments
from X-RAYS poisoning: Cadm-s. cob. m-aust. phos. rad-br. sol sulph. uran-n.
x-ray
Toxicity: ailments
from RADIATION: sickness, poisoning: burns: alf. Ars. Cadm-i. Cadm-s. calc-f. Calen.
canth. caust. Chin. Com-met. fl-ac. Hydr. Ip. Nux-v. phos. rad-br. Sil. Sol. Stront-c.
Uran-n. x-ray.
Stomach: NAUSEA,
general: radiation, treatment from: ars. Cadm-s. ip. nux-v. sol
STOMACH: ULCERS:
radiation treatment for acne, after: phos.
STOMACH: ULCERS
after radiation treatment for acne: phos.
CHEST: CANCER:
ulcerating, mammae: surgery, radiation, after: hippoz.
CHEST: CANCER
in Mammae + pain after radiation: hippoz. streptom.
Skin: INFLAMMATION:
radiation, dermatitis: cadm-s. rad-br. x-ray
SKIN: ULCERS:
necrosis: radiation therapy; from: cadm-i.
BURNS,
fire, chemicals, ailments from radiation: calc-f. calen. fl-ac. phos. rad-br.
Sol x-ray
Cancer: WEAKNESS,
with cancer after radiation therapy: alf. Cadm-s. sol
Cancer: RADIATION,
sickness, for side effects: alf. ars. BISM. Cadm-i. CADM-S. calc-f. calen. Canth.
Caust. chin. cob. Fl-ac. hydr. Ip. nux-v. Phos. rad-br. sil. SOL Stront-c.
uran-n. x-ray
Cancer: CACHEXIA,
emaciation with cancer: radiation, therapy, from: alf. ars. CADM-S. calc-f.
chin. fl-ac. hydr. Ip. nux-v. phos. rad-br. sil. SOL x-ray
EXTREMITIES:
PAIN: rheumatic: radiation therapy; after: rad-br.
Bones: SOFTENING,
bones: radiation, x-rays, from: cadm-met. cadm-s. cortico. cortiso. rad-br.
GENERALITIES:
RADIATION, sensation of background: tax.
GENERALS: WEAKNESS:
radiation therapy; from: rad-br.
GENERALS: ULCERS:
radiation therapy; from: rad-br.
GENERALS: RADIATION
THERAPY; from: abrot. Alf. ars-br. ars. Bism-met. cadm-i. cadm-met. cadm-s.
calc-f. calc-sil. calen. Canth. Caust. chin. Cob-met. cob-n. ferr-sil. fl-ac.
germ-met. Hippoz. ip. irid-met. kali-bi.
kali-p.
kali-sil. lith-f. lith-m. lith-met. lith-p. lith-s. mag-sil. mang-sil. M-aust. nat-sil. nux-v. phos. plut-n.
rad-br. sil-met. sil. sol Streptom. stront-c. Sulph. Tax. Uran-n. x-ray
GENERALS: ailments
during CONVALESCENCE after radiation therapy: cadm-s.
Vorwort/Suchen Zeichen/Abkόrzungen Impressum