‡ By: Otto Wolff, M.D.
It seems that people have always been looking for refreshment to overcome tiredness. Vegetable stimulants were used for the purpose. All of those plants were found to contain Coffin. as the stimulant.
(all coffeine-producing plants grow in hot climates).
"1st generation" stimulant drinks are Coff. (1 - 2%/Abyssynian highlands)/Tea (4.3%/area between India and China)/Mate (1,25%/region of the Parana River in S.America)/Guar. (4,2%/near the Orinoco River)/
Kola (1 - 2%/tropical Africa).
Animals do not use these plants for their stimulant effect/it must be a typically human desire to be wholly awake and in full conscious awareness. Not only were the plants and the parts to be used discovered but special methods of preparation have been developed (roasting of coffee beans/fermentation of tea leaves).
"2nd generation" of stimulant drinks was produced in industrial scale. Coca cola = combination Coffin + Coca leaf extract. The coca shrub native of tropical S.America. The locals chew the leaves which are said to "satisfy the hungry, give new energy to the tired, and make people forget their misery“. Originally they were used in rituals in Peru, with serious penalties exacted for profane use. The main active principle is cocaine = chemically similar to the Atrop. with totally different effects.
The cola drinks sold do not carry a full declaration of ingredients but are said not to contain cocaine today. The term "vegetable extracts" tells us very little.
Phosphates also have other, deep-reaching effects (as in the hyperkinetic syndrome). Colas are hot favorites -though drunk cold- throughout the civilized world today, indicating a general desire to overcome physiological tiredness and be wide awake and high-level performers.
"3rd generation" drinks have now appeared which contain taurine as a new active principle.
First Red Bull. The declared composition is practically the same for all these drinks. Again, sugar (circa 10%) and Coff. are the basis, though compared to cola drinks the caffeine concentration is much higher at 320 mg/liter (according to a Coca Cola distribution center, the concentration in Coca Cola is between 65 and 250 mg/liter, which is the highest concentration permitted in Germany).
The manufacturers have found a way of going above the legal limit for caffeine in lemonades, using 320 mg/liter, and to introduce taurine, though this is not officially permitted. Red Bull is thus currently produced and marketed in Austria/Germany/Hungary/Britain.
The new ingredient is taurine, and propaganda is made with this in the declaration. They have become known within a short time, initially without advertising (!), and consumption is obvious high.
Why taurine? The compound results from decarboxylation of cysteine, a degradation product of the disulfide cystine. This is a sulfur-containing amino acid of vital importance not only for anabolism but above all in detoxification processes.
Decarboxylation is the general route by which biogenic amines are produced from amino acids. The amines are instruments of astral activity and connected with processes of conscious awareness. However, due to the sulfur component and a chemical constitution that is very simple compared to other biogenic amines, this activity is at a low level. The powerful oxidation involved in conversion of cysteine to taurine is worth noting, however. It is characteristic of humans and animals, that is, life at the level of spirit and soul. Oxidation connects substances with the earth, also a function of the iron-bile impulse which is the physiological basis of mental and spiritual activity.
Taurine thus relates mainly to a biliary process, which is also evident from its industrial role: it is synthesized mainly for the manufacture of detergents. The compound acts as an emulsifier (a characteristic
Taurine bound to bile acids and excreted as taurocholic acid. The acid was first found in ox bile, hence its name (tauros = bull). It was found that humans excrete about 3x glycocholates than taurocholates.
Some carnivores (dogs) excrete only taurocholates/also predominating in other predators.
"According to the German Federal Department of Health, low concentrations of the amino acid (sic) taurine
(= part of Lac-h.), which promotes numerous metabolic processes in human metabolism, have been added to baby foods for years“. Clearly, neither the author passing the information nor the Department knew that taurine is not an amino acid and had no idea which metabolic processes in infants are involved.
All bile acids derived from degradation of cholesterol, a slightly soluble compound. In a number of steps,
2 primary bile acids are produced in the liver: cholic acid and chenodeoxycholic acid. The resulting chenodeoxycholic acid (cheno acid in short) is found mainly in the bile of geese, but also in human bile. It is freely soluble and also dissolves gallstones, having been used for this purpose since 1975. Its emulsifying power is greater than that of other bile acids (Chenofalk®). Healthy bile will dissolve gallstones because it contains the relevant bile acids.
Ursodeoxycholic acid is much the same. As the name indicates it was found in the bile of bears, used for centuries in Chinese medicine. Its cholagogue properties make it particularly useful in cholestasis (cirrhosis) (Urofalk®). Lithocholic acid (lithos = stone; 3-monohydroxycholanic acid), which is only slightly soluble, is the product of microbial reduction of the two OH groups at 7 and 12 of cholic acid or the 7-OH of cheno acid (secondary bile acids) in the intestine.
This indicates the role of the intestinal flora in gallstone development. Bacterial metabolism always reductive, the biliary process oxidative. If unphysiological and perhaps even aggressive bacterial activity predominates over bile production, degradation of primary bile acids increases and lithocholic acid (= a bile acid that acts as a detergent to solubilize fats for absorption. It is made from chenodeoxycholic acid by bacterial action in the colon. It has been implicated in human and experimental animal carcinogenesis.
Dietary fiber can bind to lithocholic acid and aid in its excretion in stool; as such, fiber can protect against colon cancer. This is withdrawn from the enterohepatic circulation
of bile acids, resulting in reduced activity.
The many other bile acids differ mainly in their degree of oxidation. They combine with glycocoll or taurine to form different conjugated bile acids. Thus glycocholic acid
is a conjugate of glycocoll (= glydne, aminoethanoic acid, NH2-CH2-COOH), the simplest amino acid and one of the bile acids. Taurocholic acid is a conjugate of taurine
and cholic acid (generally) or deoxycholic acid.
Taurine and glycine are eliminated in conjugated form via the liver and bile and resorbed, thus stimulating bile formation.
The function of the hepatobiliary system is to "make idea into reality“, with bile formation providing the necessary activity by transforming the stream of substances produced in me liver. The significance of bile formation (bile acid production), thus lies not only in the physiological function of fat emulsification to facilitate absorption but in providing a physical basis for activity at the level of spirit and soul. The enterohepatic circulation of bile acids plays a major, constitution-determining role in this. This is essentially the origin of the choleric temperament, with cholerics clearly bile-determined, active individuals.
The bile-stimulating activity of bile acids also has a qualitative aspect. Activities of spirit and soul can intervene powerfully yet gently, with due regard for existing conditions, or they may be uncontrolled and aggressive. Much can be learned from the fact that different animals have greatly different biliary products, with taurocholic acid predominant in carnivores (dogs/predators). Aggressiveness is a dominant characteristic of these animals. As shown above, taurocholic acids should be in a lower proportion than glycholic acids in humans.
In other words, taurine stimulates bile formation, leading to increased activity, but qualitatively speaking this is more animal-like and aggressive. The extent to which such massive stimulation is still controllable and, indeed, in accord with human nature remains to be seen.
Earlier investigations have shown that human, porcine and bovine bile = Fel tauri depuratum have hypotensive properties. The action is less powerful in canine bile. Even sodium salts in isolated glychocholic and taurocholic acid still have hypotensive activity, though the duration and intensity of action were much greater in purified dried ox bile. Cholic acid is listed as a choleretic in the 1993 drugs list published by the German Federal Association of Pharmaceutical Concerns (= Rote Liste), with products mentioned including NovoMandrogallan (contains Fel tauri and cholic acid) and the tonic Glutergen +H3, but the superior activity of dried bile (Fel tauri) with its hypotensive action is no longer utilized. Not one of the many antihypertensives listed includes Fel tauri. in spite of the physiological data available goose bile, for instance, has never been used to dissolve bile stones. The isolated prindple is given preference.
It would be well worthwhile doing a Goethean study to determine the quality of bile produced by different animals. This may also provide a basis for differentiated clinical use. The relevant analyses have been done.
Another declared ingredient of the new drinks is inositol, C6H6 (OH)6. This is glucose-like, sweet-tasting, and found practically everywhere in the biological sphere, above all in muscle tissue (myo-inositol)/brain/liver/lung/milk/cereal grains mostly in combination with Phos-ac. as phytin (hat komplexbildenden Eigenschaften/kann mit der Nahrung aufgenommene Mineralstoffe (Ca/Mg/Fe/Zn) unlöslich binden). The inositol phosphatide is found mainly in soy/brain tissue. Inositol has a specific relationship to phosphorus and phosphoric acid. As previously shown, phosphorus stimulates ego activity in metabolism (in conjunction with sugar/sugar-like compounds such as inositol) which may result in hyperkinetic syndrome.
Apart from Coffin./taurine/myo-inositol/glucurolactone is mentioned as an ingredient of the drinks. This is an intermediate product between glucose and vitamin C. It is now known that humans are not able to produce vitamin C from glucose themselves. Glucoronic acid does, however, have an important detoxification function. It forms watersoluble glucuronides that are eliminated mainly in the bile, ultimately again stimulating biliary function.
Most of the B groups of vitamins have been acided, which makes sense as they are needed for energy-consuming activities (vitamin B1 = "nerve vitamin"). This actually makes it possible to abuse the ether body by increasing external activity, temporarily compensating it to permit further "activity“. Yet even the coca leaf chewing Indians knew that in the long run this depletes the body. Excessive Cofin. consumption ("natural form" as Coff./Tea etc./acided to soft drinks) leads to exhaustion (nervous system) with sleeplessness. People who have extremely good livers (young people) are able to compensate for a long time, which is part of the nature of
the thing but does not change the principle.
The question is, why do young people in particular have such a need for stimulant effects? As already stated, powerful conscious awareness is part of human nature. It is generally known and "proven" that this can be stimulated by Coff. This is where taurine appears on the scene, effecting choleresis. The resulting need to
be active is exactly what we see in many young people. This is the "switched-off" generation which feels life offers little that is of interest and needs its "kicks" which are gained through exciting situations such as
a football game/a thriller/a medicinal impulse given to biliary function. With the "brilliant" combination of stimuli given to the conscious mind and the will, people feel STRONG. This enhances self awareness of the kind achieved with drugs (heroin). It is not real strength but an illusion, but those concerned are unable to realize this. The same applies to sugar consumption
In reality, all external stimuli are liable to make people unfree and weak; they are then dependent and may ultimately become acidicts - the foundations for this are certainly laid. Genuine strength develops only
through inner activity and work.
It needs a true science for a human being to realize that the (desired) stimulation of conscious awareness
(more than wide awake) and will (hyperactivity), which then go directly hand in hand, eliminates or at least neglects the middle element of feeling and, therefore, the truly human aspect. Real feeling coming from the heart that may also engender enthusiasm is generally looked down upon. We are "cool" today, not showing - or indeed developing - emotions. This allows a logical, intellectual thought that is not controlled by any moral quality to enter directly into a will impulse and action. Daily life provides sufficient examples of this.
Although problems arise with these stimulant effects, we certainly do not have to do without them if they are used for particular occasions (a cup of coffee or tea in the mornings or at conferences) and within limits;
but repeatedly consuming them in excess can lead to dependence which ultimately means physical or mental and spiritual weakening of the individual. ‡